Morning sickness

It's as much a part of pregnancy as painting the nursery

Nausea and vomiting are common in early pregnancy, affecting 70% to 85% of moms-to-be.1

Once pregnancy-associated symptoms of nausea and vomiting progress, treatment can become challenging. Therefore, treatment in the early stages can be beneficial in supporting a healthy pregnancy.2

Vitamin B6 is recommended by the American Congress of Obstetricians and Gynecologists (ACOG) as a safe and effective first-line treatment for pregnancy-related nausea and vomiting.2

Vitamin B6 is good for moms. And it's essential for babies.

For all it does to help expectant moms with morning sickness, vitamin B6 is even more important in fetal development, playing a key role in3:

  • Normal physiological function
  • Supporting macronutrient metabolism
  • Red blood cell, antibody, and neurotransmitter synthesis

For this reason, it is also vital to fetal brain and nervous system development.4

PreferaOB ONE® has the vitamin B6 found in other prenatal vitamins. And then some.

Most prenatal vitamins contain vitamin B6. However, their concentrations of B6 are typically not high enough to address the morning sickness many expectant moms experience. At 50 mg, PreferaOB ONE® has one of the highest doses of vitamin B6 available in a prenatal vitamin, so mom and baby are provided for.1,2

INDICATIONS AND USAGE: PreferaOB ONE® is a prescription multivitamin/multimineral nutritional supplement with Omega-3 fatty acid (life'sDHA™) indicated for use in improving the nutritional status of women throughout pregnancy and in the postnatal period for both lactating and non-lactating mothers. PreferaOB ONE® is also beneficial in improving the nutritional status of women prior to conception.


WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

CONTRAINDICATIONS: This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

WARNING: Ingestion of more than 3 grams of Omega-3 fatty acids per day has been shown to have potential antithrombotic effects, including an increased bleeding time and International Normalized Ratio (INR). Administration of Omega-3 fatty acids should be avoided in patients taking anticoagulants and in those known to have an inherited or acquired predisposition to bleeding diathesis.

PRECAUTIONS: Folic acid when administered as a single agent in doses above 0.1 mg daily may obscure pernicious anemia in that hematological remission can occur while neurological manifestations remain progressive. Pregnant women and nursing mothers should avoid supplemental doses of vitamin E higher than RDA amounts. While prescribing this nutritional supplement for pregnant women, nursing mothers, or for women prior to conception, their medical condition and other drugs, herbs, and/or supplements consumption should be considered.

ADVERSE REACTIONS: Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit or call 1-800-FDA-1088.

Please see Full Prescribing Information.


1. Davis M. Nausea and vomiting of pregnancy: an evidence-based review. J Perinat Neonatal Nurs. 2004;18(4): 312-328. 2. American College of Obstetrics and Gynecology. ACOG (American College of Obstetrics and Gynecology) Practice Bulletin: nausea and vomiting of pregnancy. Obstet Gynecol. 2004;103(4):803-814. 3. Office of Dietary Supplements. National Institutes of Health. Dietary supplement fact sheet: vitamin B6. Updated September 15, 2011. Accessed December 7, 2011. 4. McArdle HJ, Ashworth CJ. Micronutrients in fetal growth and development. Br Med Bull. 1999;55(3):499-510.